swi5 — Schizosaccharomyces pombe 972h-

Summary

SPBC409.03 (swi5) on chromosome 2 of Schizosaccharomyces pombe encodes a Swi5-family protein with ATPase activator activity and identical protein binding. The gene product is associated with meiotic DNA recombinase assembly, meiotic strand invasion, joint molecule formation, and resolution of recombination intermediates. It is linked to mating-type switching, gene conversion at the mating-type locus, donor selection, and karyogamy. Additional associations include heterochromatin organization, microtubule nucleation, prophase, and recombinational repair. The protein localizes to the nucleus, nuclear chromosome, and mating-type region heterochromatin. Studies of related genes in other species link the Swi5 family to the Swi5-Swi2 and Sae3-Mei5 complexes.