ADH1 — Schizosaccharomyces pombe 972h-

Summary

SPBC337.11 (ADH1) on chromosome 2 of Schizosaccharomyces pombe encodes a zinc-type alcohol dehydrogenase-like protein with aldo-keto reductase (NAD) activity and oxidoreductase activity acting on NAD(P)H and CH-OH group donors. The gene is associated with ethanol fermentation, malolactic fermentation, malate transport, and fermentation, as well as with pheromone response, mating, meiosis, sporulation, cell differentiation, and gene conversion. It is also linked to DNA repair, homologous recombination, regulation of gene expression, secretion, regeneration, and response to zinc. The product localizes to the cytoplasm, nucleus, membrane, mitochondrial lumen, and fungal biofilm matrix. Related genes in other species link the family to oxidoreductase activity (EC 1.1.1.1).