cdc8 — Schizosaccharomyces pombe 972h-

Summary

SPAC27F1.02C (cdc8) in Schizosaccharomyces pombe 972h- on chromosome 1 encodes a tropomyosin family protein. The gene is associated with actin lateral binding and F-actin binding. It is linked to actin depolymerization and polymerization, actin cortical patch organization, mitotic actomyosin contractile ring assembly and contraction, and mitotic cytokinesis. It is associated with maintenance of cell polarity, cell polarization, interphase, spore germination, sexual reproduction, pheromone response, vacuole fusion, gene conversion, and nucleotide metabolism. The product localizes to F-actin, actin patches, formin-nucleated actin cables, the mitotic actomyosin contractile ring, the cell division site, the mating projection tip and fusion focus, and the cytoplasm.