shu1 — Schizosaccharomyces pombe 972h-

Summary

SPAC1F8.02C (shu1) in Schizosaccharomyces pombe 972h- encodes a protein with heme receptor activity and heme binding. The gene is associated with heme import into the cell, heme transport, and cellular response to iron ion starvation, as well as iron transport and response to iron. It has been linked to DNA damage tolerance, homologous recombination, the TCA cycle, cell growth, and homeostasis. The product localizes to the external side of the plasma membrane, the vacuolar membrane, and the fungal-type vacuole.