MID1 — Schizosaccharomyces pombe 972h-

Summary

SPAC1F5.08C (MID1, yam8) on chromosome 1 of Schizosaccharomyces pombe 972h- encodes a member of the Mid1/Ehs1 protein family and has calcium channel activity. The gene is associated with calcium ion import into the cell, regulation of cell division and cytokinesis, division plane positioning, contractile ring assembly, spindle breakdown, spindle assembly checkpoint, microtubule dynamics and shortening, and the septation initiation network (SIN). It is also linked to photosynthesis, FAD transport, bioluminescence, centromere separation, angiogenesis, and cellular localization. The product localizes to the plasmalemma and membrane. Additionally, MID1 has been connected to acid sensitivity. Studies of related genes in other species, including calcium channel subunit Mid1 and calcium influx-promoting protein ehs1, link the family to calcium signaling and cell division processes.