SSO1 — Saccharomyces cerevisiae S288c

Summary

YPL232W, also known as SSO1, encodes a syntaxin-family SNARE protein on chromosome XVI of Saccharomyces cerevisiae S288c. The gene product is a SNARE that mediates SNARE binding and is a core component of the SNARE complex. SSO1 is associated with vesicle fusion, vesicle docking, membrane docking, and SNARE complex assembly, as well as secretion, endocytosis, and endocytic recycling. It has been linked to nuclear division, meiosis, sporulation, and spindle pole body assembly. The protein localizes to the prospore membrane leading edge, plasma membrane raft, endomembrane system, endosome, Golgi complex, and extracellular vesicles. SSO1 is associated with traits including sporogenesis and phenotypes such as absent protein secretion and sporulation, decreased chronological lifespan, decreased vegetative growth, altered metal and chemical resistance, and increased filamentous growth. Studies of related genes in other species link the family to similar membrane trafficking processes.