TCO89 — Saccharomyces cerevisiae S288c

Summary

YPL180W encodes a component of the TORC1 complex, specifically the TCO89 subunit. The gene is associated with a wide range of biological processes, including cellular amino acid homeostasis, glutamine and aromatic amino acid anabolism, autophagy, endocytosis, the multivesicular body sorting pathway, neutral lipid and triglyceride metabolism, and TORC2 signaling. It is also linked to the regulation of translation and responses to amino acids. Phenotypically, YPL180W is associated with altered stress resistance, including increased tolerance to oxidative stress, heat, and metals, as well as decreased resistance to toxins and hydrostatic pressure. Other associations include abnormal cell wall morphology, increased cell size, altered sporulation efficiency, and changes in carbon and nitrogen source utilization. The gene is also linked to traits such as salt tolerance, phosphate content, and sensitivity to light and acid.