ATF1 — Saccharomyces cerevisiae S288c

Summary

YOR377W in Saccharomyces cerevisiae S288c encodes an alcohol O-acetyltransferase, a member of the Atf2/Sli1-like family. The gene is associated with the metabolism of acetate esters, including ethyl acetate and geraniol, as well as pheromone anabolism and acetate fermentation. It is linked to the regulation of fatty acid metabolism and fatty acid homeostasis, and to responses such as glucose detection, detoxification, and the SAPK signaling pathway. Associations with traits include salt tolerance and oxidative stress. Observed phenotypes link the gene to decreased sporulation, altered chemical compound excretion, reduced heat sensitivity, decreased vegetative growth, and decreased competitive fitness, though the gene is also associated with normal competitive fitness and viability.