YNR071C — Saccharomyces cerevisiae S288c

Summary

YNR071C (GAL10) on chromosome XIV of Saccharomyces cerevisiae S288c encodes a protein with UDP-glucose 4-epimerase and aldose 1-epimerase activities, and is also a member of the aldose 1-epimerase family. The gene is associated with UDP-galactose biosynthesis, monosaccharide and lactose metabolism, carbohydrate anabolism, and starch and lysine breakdown. It is linked to fruit development, morphogenesis, response to host, xenobiotic metabolism, and carotene anabolism. Localisation evidence connects the product to the cytosol and extracellular space. The gene is associated with traits including herbicide sensitivity, copper concentration, biomass yield, salt tolerance, and oxidative stress, as well as phenotypes of haploinsufficiency, decreased competitive fitness, viability, and decreased resistance to chemicals. Studies of related genes in other species link the family to galactose mutarotase function and EC numbers 5.1.3.2 and 5.1.3.3.