FPS1 — Saccharomyces cerevisiae S288c

Summary

YLL043W encodes a glycerol and water channel protein belonging to the MIP/aquaporin family. The gene product is associated with the plasma membrane and is linked to diverse biological processes including mRNA transcription, glutathione anabolism, ethanol fermentation, the TCA cycle, vacuolar acidification, protein import and prenylation, and responses to ethanol and yeast. It is associated with intracellular glycerol accumulation, arsenite and water transport, and pH reduction. Phenotypic associations include decreased resistance to hypo- and hyperosmotic stress, desiccation, UV, and oxidative stress, as well as increased fermentative metabolism, altered metal resistance, and reduced replicative and chronological lifespan. The gene is also linked to traits such as root length, turgor pressure, salt sensitivity, and biomass yield.