YLL039C — Saccharomyces cerevisiae S288c

Summary

YLL039C in Saccharomyces cerevisiae S288c encodes a protein with ubiquitin-like domains and exhibits enzyme inhibitor activity, protein tag function, and ubiquitin ligase binding. The gene is associated with proteasome degradation, amino acid import and transport, protein modification, stress response, meiotic cell cycle regulation, telomere maintenance, translation initiation, and secretion. It localizes to the cytoplasm and nucleus. Phenotypic associations include decreased viability, sporulation absence, reduced spore germination, decreased replicative and chronological lifespan, altered thermotolerance, increased apoptosis, decreased oxidative stress resistance, reduced UV and desiccation resistance, decreased starvation and stress resistance, increased vegetative growth rate, and abnormal redox state. The gene is also linked to light sensitivity, acid sensitivity, and oxidative stress. Related genes in other species connect the family to similar cellular processes.