TRK2 — Saccharomyces cerevisiae S288c

Summary

YKR050W in Saccharomyces cerevisiae S288c encodes a protein with high-affinity potassium ion transmembrane transporter activity, chloride transmembrane transporter activity, and chloride channel activity. It belongs to the Trk/HKT potassium transporter family. The gene is associated with potassium ion import across the plasma membrane, chloride transport, cell volume homeostasis, regulation of membrane potential, membrane hyperpolarization and depolarization, cellular response to cation stress, pH reduction, cytoskeleton organization, intracellular sterol transport, and glucose and amino acid breakdown. It localizes to the plasma membrane, cell tip, cell division site, Golgi complex, and chloride channel complex. Associations with traits include potassium content and uptake, sodium uptake, turgor pressure, salt sensitivity, germination rate, and oxidative stress. Phenotypic associations link the gene to decreased osmotic and ionic stress resistance, increased biofilm formation and metal resistance, and abnormal vacuolar morphology.