RSF2 — Saccharomyces cerevisiae S288c

Summary

YJR127C from Saccharomyces cerevisiae S288c encodes a C2H2-type zinc-finger transcription factor with DNA-binding transcription repressor and activator activities, RNA polymerase II-specific. The protein localises to the nucleus, nucleoplasm, chromatin, heterochromatin, cytoplasm and cytosol. YJR127C is associated with glucan and ubiquinone anabolism, siderophore anabolism, fatty acid oxidation, regulation of gluconeogenesis, negative regulation of flocculation, cell wall thickening, and positive regulation of cell-substrate adhesion and biofilm formation. It is linked to responses to water, methanol, salt, salinity, oleate and oxidative stress, as well as to glucose content and acid sensitivity. Phenotypic associations include decreased acid pH resistance, altered chronological lifespan, decreased nitrogen source utilisation, decreased toxin resistance, altered competitive fitness, abnormal vacuolar morphology, and altered chemical resistance.