IME1 — Saccharomyces cerevisiae S288c

Summary

YJR094C, also known as IME1, is a gene on chromosome X of Saccharomyces cerevisiae S288c. The IME1 product is associated with the meiotic cell cycle, including meiotic S phase, meiotic chromosome segregation, prophase, leptotene, nuclear division, and activation of meiosis. It is linked to spore formation, ascus development, spore dispersal, and regulation of sporulation. The gene has been connected to developmental growth, cell quiescence, response to nutrient levels, response to basic pH, sensory transduction, DNA anabolism, and methylation. Phenotypic associations include altered sporulation efficiency (both increased and decreased), absent sporulation, increased mitotic recombination, altered RNA and protein accumulation, abnormal protein distribution, decreased utilization of nitrogen source, decreased metal and chemical resistance, increased competitive fitness, and haploid insufficiency.