ERG20 — Saccharomyces cerevisiae S288c

Summary

YJL167W, also known as ERG20 or FPS1 in Saccharomyces cerevisiae S288c, encodes a protein with geranyltranstransferase, dimethylallyltransferase, and farnesyltranstransferase activities, and it binds metal ions. This enzyme is associated with the biosynthesis of numerous isoprenoid compounds, including geranylgeranyl diphosphate, farnesyl diphosphate, geraniol, limonene, carotenoids, dolichol, polyprenol, and terpenes, as well as protein prenylation. It has been linked to processes such as pentose catabolism, intracellular glycerol accumulation, arsenite and water transport, and the production of viridicatumtoxin. The gene product localizes to the endoplasmic reticulum, cytoplasm, cytosol, nucleus, and fungal biofilm matrix. Associations with traits including root length, turgor pressure, salt sensitivity, biomass yield, and oxidative stress have been noted, along with phenotypes such as altered chemical compound excretion and accumulation, auxotrophy, inviability, and changes in vegetative growth and competitive fitness.