YHR210C — Saccharomyces cerevisiae S288c

Summary

YHR210C in Saccharomyces cerevisiae S288c encodes a protein with UDP-glucose 4-epimerase and aldose 1-epimerase activities, and is also associated with sugar binding. The gene is linked to a wide range of biological processes, including lysine breakdown, ribosomal skipping, platelet aggregation, receptor breakdown, xenobiotic metabolism, carbohydrate anabolism, starch breakdown, fruit development, cytochrome anabolism, monosaccharide metabolism, lactose metabolism, UDP-galactose biosynthesis, response to host, fructose uptake, transcriptional readthrough, carotene anabolism, DNA integration, and galactose breakdown. It is localized to the extracellular region and cytosol. The gene is associated with traits such as herbicide sensitivity, copper concentration, biomass yield, salt tolerance, and oxidative stress. Phenotypic associations include decreased sporulation efficiency, decreased oxidative stress resistance, decreased vegetative growth rate, abnormal vacuolar morphology, and decreased competitive fitness. Studies of related genes in other species link the family to galactose mutarotase and EC numbers 5.1.3.2 and 5.1.3.3.