ATG32 — Saccharomyces cerevisiae S288c

Summary

YIL146C in Saccharomyces cerevisiae S288c encodes a protein of unknown molecular function, but it is associated with a wide range of cellular processes and traits. The gene is linked to spermidine metabolism, polyamine anabolism, mitochondrial fission, mitophagy, pexophagy, macroautophagy, ethanol fermentation, and the electron transport chain. It localizes to the PAS membrane, mitochondrial outer membrane, and vacuolar membrane. Associations with traits include biomass yield, oxidative stress, and acid sensitivity. Phenotypic connections include delayed vegetative growth, increased fermentative growth, altered mitophagy, decreased respiratory growth, increased replicative lifespan, and altered resistance to toxins, metals, and heat. Related genes in other species link this family to reduced virulence.