SUC2 — Saccharomyces cerevisiae S288c

Summary

YIL162W (INU1, SUC2) on chromosome IX of Saccharomyces cerevisiae S288c encodes a beta-fructofuranosidase with inulase and fructan exohydrolase activity. The gene is associated with inulin and sucrose metabolism and breakdown, raffinose breakdown, fructose uptake, and the Leloir pathway. It has been linked to heterotrophy, social behavior, glucose effect, regulation of gene expression, rhamnolipid biosynthesis, triglyceride mobilization, and polyol anabolism. The product localizes to the fungal-type vacuole, extracellular space, cytoplasm, cytosol, and nucleus. Associations with traits include water use efficiency, oligosaccharide and sugar content, carbohydrate content, biomass yield, and oxidative stress. Phenotypic connections include altered nutrient utilization, fermentative metabolism, carbon source utilization, stress resistance, vegetative growth rate, vacuolar morphology, competitive fitness, and chemical resistance. Studies of related genes in other species link the family to inulinase and invertase activities.