GRE3 — Saccharomyces cerevisiae S288c

Summary

YHR104W, also known as GRE3, encodes an aldo/keto reductase family protein with D-xylose:NADP reductase activity and mRNA binding. In Saccharomyces cerevisiae S288c, this gene is associated with diverse metabolic processes including methylglyoxal metabolism, the Leloir pathway, galactose metabolism, xylulose anabolism, and D-xylose fermentation. It is linked to stress responses, including response to oxygen levels and methylglyoxal, as well as acetate fermentation, homologous recombination, and lignin breakdown. Associations with agronomically relevant traits include sucrose content, sugar content, biomass yield, and oxidative stress. Phenotypic associations include altered fermentative growth, carbon source utilization, protein activity, chronological lifespan, and competitive fitness. Studies of related genes in other species link the family to EC 1.1.1.307.