HXT1 — Saccharomyces cerevisiae S288c

Summary

YHR094C (HXT1) on chromosome VIII of Saccharomyces cerevisiae S288c encodes a protein with hexose transmembrane transporter activity, gluconate transmembrane transporter activity, high-affinity glucose:proton symporter activity, galactose transmembrane transporter activity, D-glucose transmembrane transporter activity, and proton:sugar symporter activity. The gene is associated with glucose import, fructose uptake, maltose and sucrose transport, D-xylose fermentation, and starch metabolism. It has been linked to ammonium excretion, response to fructose, farnesol and riboflavin anabolism, regulation of histidine anabolism and ribosome biogenesis, and chitosamine metabolism. Localization evidence connects the product to the plasma membrane, cell tip, cell division site, fungal-type vacuole, mitochondrial membrane, and cytoplasm. The gene is associated with traits including sucrose content and biomass yield, and with phenotypes such as altered vegetative growth, lifespan, chemical resistance, competitive fitness, vacuolar morphology, and small molecule transport. Related genes in other species are linked to oxidative stress.