AFT1 — Saccharomyces cerevisiae S288c

Summary

YGL071W encodes the Aft1 protein in Saccharomyces cerevisiae S288c, a member of the AFT domain family. The gene is associated with cellular response to HU, oxygen transport, response to HU, deoxyribonucleotide anabolism, iron-sulfur cluster assembly, glutathione anabolism, siderophore transport, response to iron, sulfur metabolism, phospholipid metabolism, iron transport, haem metabolism, TCA cycle, response to stress, response to yeast, regulation of Fe transport, cellular response to iron, and carbohydrate metabolism. It is linked to iron sensitivity, cobalt sensitivity, zinc sensitivity, iron concentration, manganese content, oxidative stress, and acid sensitivity. Phenotypic associations include altered small molecule transport, growth in exponential phase, RNA accumulation, utilization of iron source, mitophagy, cell cycle progression in G1 phase, respiratory growth, protein activity, alkaline pH resistance, cell size, mitochondrial morphology, utilization of carbon source, replicative lifespan, colony sectoring, metal resistance, UV resistance, protein/peptide accumulation, hyperosmotic stress resistance, chromosome/plasmid maintenance, chronological lifespan, oxidative stress resistance, and vegetative growth.