CDC55 — Saccharomyces cerevisiae S288c

Summary

YGL190C, also known as CDC55, encodes a protein with protein phosphatase regulator and activator activity in Saccharomyces cerevisiae S288c. The gene is associated with the PP2A complex and localizes to the mitotic spindle, spindle pole body, and cytosol. CDC55 is linked to meiotic exit, vacuolar localization, MAD, microautophagy, spindle elongation, mitotic checkpoint, spindle assembly checkpoint, spindle checkpoint, regulation of fumonisin anabolism, response to nutrient, mitotic exit, ubiquitin-dependent proteolysis, TOR signaling, cell morphogenesis, meiosis I, response to methionine, spindle assembly, and nuclear division. Phenotypic associations include abnormal meiosis, decreased chromosome segregation and cytokinesis, increased cold sensitivity and oxidative stress resistance, and changes in biofilm formation, filamentous growth, and pseudohyphal growth. The gene is also linked to salt sensitivity and oxidative stress.