GAT1 — Saccharomyces cerevisiae S288c

Summary

YFL021W, also known as GAT1, encodes a GATA-family transcription factor that localises to the nucleus and binds sequence-specific DNA via a zinc-finger domain. It is associated with the regulation of nitrogen metabolism, including nitrate assimilation, glutamate and glutamine anabolism and breakdown, and the GABA shunt. The gene is linked to responses to rapamycin, methionine, and nickel, as well as to ether lipid, glycerolipid, and phosphatidic acid anabolism. Associations with traits include carbohydrate content, oxidative stress, and salt tolerance. Phenotypic associations link GAT1 to altered chemical compound accumulation, increased or decreased competitive fitness, reduced vegetative growth rate, abnormal vacuolar morphology, and altered stress resistance. Related genes in other species are linked to reduced virulence.