CTA1 — Saccharomyces cerevisiae S288c

Summary

YDR256C (CTA1) in Saccharomyces cerevisiae S288c encodes a catalase with heme-binding and metal-binding activity, localizing to the peroxisomal lumen, peroxisome, mitochondria, cytoplasm, and fungal-type cell wall. This gene is associated with response to oxidative stress, cellular detoxification of hydrogen peroxide, hydrogen peroxide metabolic process, DNA damage response, signal transduction, cell killing, regulation of response to stress, lipid metabolism, maltose metabolism, vitellogenesis, sleep, chromosome localization, and responses to oleate. It is linked to traits including oxidative stress and carbohydrate content, and phenotypes such as decreased oxidative stress resistance, decreased desiccation resistance, decreased hyperosmotic stress resistance, decreased innate thermotolerance, decreased competitive fitness, decreased survival rate in stationary phase, increased chronological lifespan, decreased autophagy, decreased carbon source utilization, abnormal vacuolar morphology, and abnormal protein/peptide distribution. Related genes in other species are linked to unaffected pathogenicity.