SNF1 — Saccharomyces cerevisiae S288c

Summary

YDR477W (SNF1) on chromosome IV of Saccharomyces cerevisiae encodes a protein with protein kinase A activity, protein serine kinase activity, protein serine/threonine kinase activity, ATP binding, and identical protein binding. It is a component of the nucleotide-activated protein kinase complex and localises to the perinuclear space, nuclear and vacuolar membranes, and the mitotic spindle pole body. The gene is associated with the regulation of gluconeogenesis, energy homeostasis, cellular respiration, the glyoxylate cycle, and responses to nutrient levels. It is linked to glycogen, galactose, starch, and mycose metabolism, as well as microautophagy, polyamine transport, lipolysis, and transsulfuration. Associations with traits include starch and sugar content, potassium and iron concentration, alkali and acid sensitivity, and oxidative stress. Phenotypic links involve increased anaerobic growth, starvation resistance, and freeze-thaw resistance, alongside altered cell cycle progression, pseudohyphal growth, and osmotic stress resistance.