FOB1 — Saccharomyces cerevisiae S288c

Summary

YDR110W in Saccharomyces cerevisiae S288c encodes a protein of unknown molecular function, with no enzyme class or molecular-function terms annotated. The gene is associated with rDNA packaging, replicative and cellular senescence, mitotic and homologous recombination, recombination within rDNA repeats, anaphase, S phase, meiosis, mitosis, ribosome biogenesis, NAD salvage, siderophore transport, response to nutrient, maltose metabolism, alkanal metabolism, and the mitochondrial unfolded protein response. It is linked to the related gene FOB1. Phenotypic associations include increased replicative lifespan, increased sporulation efficiency, increased viability, decreased mitotic recombination, increased meiotic recombination, decreased chronological lifespan, decreased vegetative growth rate, decreased competitive fitness, altered protein/peptide accumulation and distribution, decreased starvation resistance, decreased chromosome/plasmid maintenance, and altered resistance to chemicals. The gene is also associated with oxidative stress.