BMH2 — Saccharomyces cerevisiae S288c

Summary

YDR099W, also known as BMH1 and BMH2, encodes a 14-3-3 family protein with protein sequestering activity in Saccharomyces cerevisiae. This gene is associated with a wide range of biological processes, including glycerol and catecholamine anabolism, exocytosis, the TCA cycle, glucose homeostasis, the stringent response, DNA damage response, regulation of carbohydrate metabolism, morphogenesis, and regulation of phosphorylation and secretion. It is linked to traits such as potassium uptake, potassium concentration, phosphate content, salt tolerance, and oxidative stress. Phenotypic associations include abnormal actin cytoskeleton and vacuolar morphology, increased invasive growth, altered chronological and replicative lifespan, decreased hyperosmotic stress resistance, and altered vegetative growth and competitive fitness. The protein localizes to the actomyosin contractile ring, cell wall, mitotic spindle midzone, telomeric region, extracellular vesicles, and cell division site.