REG1 — Saccharomyces cerevisiae S288c

Summary

YDR028C, also known as REG1, encodes a protein with protein phosphatase regulator activity in Saccharomyces cerevisiae S288c on chromosome IV. The gene is associated with carbon catabolite repression, glucose metabolism, and the response to glucose and nutrients. It is linked to proteasome degradation and assembly, protein modification, dephosphorylation, cell morphogenesis, invasive growth, and nuclear import. REG1 is associated with traits including biomass yield, phosphate content, potassium concentration, and oxidative stress. Phenotypic associations include increased respiratory metabolism and pseudohyphal growth, decreased fermentative metabolism and protein transport, increased desiccation resistance, altered cellular and lipid particle morphology, increased cold sensitivity, decreased replicative lifespan, and increased chronological lifespan. The protein localises to the protein phosphatase type 1 complex, the fungal-type vacuole membrane, the cytoplasm, and the cytosol.