PHO2 — Saccharomyces cerevisiae S288c

Summary

YDL106C in Saccharomyces cerevisiae S288c encodes a protein that contains a homeobox DNA-binding domain, placing it in the homeobox transcription factor family. The gene is associated with a wide range of biological processes, including phosphorus and phosphate metabolism, NAD metabolism and salvage, response to amino acid starvation, calcium signaling, cell cycle control, protein folding, and response to aluminum and basic pH. Phenotypically, YDL106C is linked to altered nutrient utilization, including decreased use of phosphorus, carbon, and nitrogen sources, as well as increased chronological and replicative lifespan, decreased freeze-thaw, desiccation, and oxidative stress resistance, increased cell size, abnormal bud morphology, delayed G1 phase progression, and decreased sporulation efficiency. The gene is also connected to traits such as carbohydrate content, calcium sensitivity, and oxidative stress.