BSC1 — Saccharomyces cerevisiae S288c

Summary

YDL037C (BSC1, also known as FLO11) on chromosome IV of Saccharomyces cerevisiae S288c is a protein of the Flo11 family. The gene is associated with a wide range of biological processes, including cell-cell self-recognition, homotypic cell adhesion, invasive growth, social behavior, and chemoaversion. It has also been linked to starch breakdown and its regulation, proline metabolism, potassium ion homeostasis, water transport, and NO storage. Phenotypic associations include increased oxidative stress resistance and competitive fitness, but decreased chronological lifespan, toxin resistance, and increased heat sensitivity. The gene is further connected to traits such as flavonoid content, iron sensitivity, potassium concentration, and salt tolerance. Studies of related genes in other species, such as SPBC1289.15.1:PEP and pfl5, link the family to additional functions, though these are not established for BSC1 itself.