PAT1 — Saccharomyces cerevisiae S288c

Summary

YCR077C, also known as PAT1, is a gene on chromosome III of Saccharomyces cerevisiae S288c that encodes an RNA-binding protein. The protein localises to the cytoplasm, cytosol, nucleus and P-bodies, and is associated with a wide range of biological processes including mRNA breakdown, deadenylation-dependent decapping, translation initiation, macroautophagy, retrotransposition, homologous recombination, and response to thiamin. Associations with traits and phenotypes include links to oxidative stress, acid sensitivity, decreased fermentative and respiratory growth, increased cold sensitivity, decreased spore germination and sporulation, increased apoptosis, decreased replicative lifespan, altered stress resistance, and changes in transposable element transposition and nutrient utilisation.