GAL1 — Saccharomyces cerevisiae S288c
Summary
YBR020W (GAL1) on chromosome II of Saccharomyces cerevisiae S288c encodes a protein with galactokinase activity and ATP binding. The gene is associated with the Leloir pathway, galactose metabolism, and a broad range of other biological processes including response to amino acids, mRNA modification, RNA retention, oxidative phosphorylation, glycogenolysis, glycerolipid anabolism, alkaloid anabolism, cell-cell signalling, short- and long-term memory, and responses to water, X-rays, and yeast. The encoded protein localises to the cytoplasm and cytosol. Associations with traits include amylose content, germinability at low temperature, male sterility, copper and iron concentration, potassium uptake, salt sensitivity, biomass yield, protein content, and oxidative stress. Phenotypic associations include decreased utilisation of carbon sources, decreased hyperosmotic and oxidative stress resistance, decreased chronological lifespan, abnormal vacuolar morphology, and altered competitive fitness.
Annotations
- Chromosome
- 2
- Related genes
- GAL1, GAL3, SPC24, YPR096C, HRB1, PGM2, HSC82, GAL80
- GO terms
- Cell Cycle, glucose effect, protein synthesis, Cell Growth, Response To Yeast, protein metabolism, Biological_Process, Membrane Fusion
- Publications
- 19214209, 9491072, 27163342, 27723736, 22445487, 19299562, 34445460, 19254955
- Traits
- RESISTANCE TO CHEMICALS: DECREASED, COMPETITIVE FITNESS: DECREASED, STRESS RESISTANCE: DECREASED, INVIABLE, RESISTANCE TO CHEMICALS: INCREASED, CELL CYCLE PROGRESSION: ABNORMAL, PROTEIN ACTIVITY: DELAYED, ENTRY INTO G0 (STATIONARY PHASE): INCREASED