GAL7 — Saccharomyces cerevisiae S288c

Summary

YBR018C in Saccharomyces cerevisiae S288c encodes a protein with UDP-glucose:hexose-1-phosphate uridylyltransferase activity and zinc binding capability. The gene is associated with the Leloir pathway, galactose metabolism, UDP-galactose biosynthesis, galactose breakdown, lactose metabolism, glycogenolysis, fermentation, carbon catabolite repression, chromatin decompaction, transcriptional readthrough, and mRNA transcription and 3'-end processing. The protein localises to the cytoplasm, cytosol, and nucleus. Phenotypic associations include altered carbon source utilization, increased biofilm formation, increased chronological lifespan, absent respiratory growth, changes in chemical compound accumulation, altered competitive fitness, decreased vegetative growth rate, and altered chemical resistance. Studies of related genes in other species link the family to the enzyme class UDP-glucose-hexose-1-phosphate uridylyltransferase (EC 2.7.7.12).