PIR32 — Neurospora crassa

Summary

NCU04033 (PIR32) on Neurospora crassa chromosome 6 encodes a protein with a Yeast_CWMannoprotein_PIR domain and a PIR1-like_C domain, classified as a structural constituent of the cell wall that binds 1,3-beta-D-glucan. The gene is associated with fungal-type cell wall biogenesis and organization, cellular response to thermal stimulus, and filamentous growth. Its product localizes to the yeast-form cell wall, fungal-type cell wall, fungal biofilm matrix, and extracellular region. Related genes in other species are linked to increased virulence and disseminated candidiasis, though these associations are not established for N. crassa.