SNF1 — Magnaporthe oryzae 70-15

Summary

MGG_00803 (MoSNF1) on chromosome 5 of Magnaporthe oryzae 70-15 encodes a serine/threonine protein kinase with protein kinase A activity, ATP binding, and phospholipid binding. The protein contains SNF1_UBA, AMPK_C, and KA1/Ssp2_C domains. MoSNF1 is associated with carbon catabolite repression, energy homeostasis, defense response, phototropism, and regulation of invasive growth in response to glucose limitation. It is linked to fungal-type cell wall assembly, septin ring assembly, and single-species surface biofilm formation. The gene is associated with blast disease in rice (Oryza sativa) and with turgor pressure. Localization evidence places the product at the nucleotide-activated protein kinase complex, cellular bud neck septin ring, nuclear membrane, and vacuolar membrane. Studies of related genes in other species link the family to reduced virulence and lethal phenotypes.