SSO1 — Magnaporthe oryzae 70-15

Summary

MoSSO1 (MGG_00978) on chromosome 5 of Magnaporthe oryzae 70-15 encodes a t-SNARE coiled-coil homology domain-containing protein with syntaxin and T_SNARE_dom domains, and is associated with SNARE binding. This gene is associated with vesicle fusion, exocytosis, intracellular protein transport, secretion, and hyphal growth. It is linked to ascospore formation, interaction with host, and lipid A and ergosterol anabolism. Localisation evidence connects MoSSO1 to the SNARE complex, endomembrane system, plasma membrane raft, prospore membrane leading edge, cell tip, and extracellular vesicle. Phenotypic associations include abnormal endoplasmic reticulum and Golgi distribution, delayed sporulation, increased mating efficiency, altered necrotic cell death, abnormal filamentous growth, and cell cycle arrest. Studies of related genes in other species link the family to reduced virulence.