VTI1 — Magnaporthe oryzae 70-15

Summary

MGG_01124 (MoVTI1) on chromosome 5 of Magnaporthe oryzae 70-15 encodes a protein containing a T_SNARE_dom and v-SNARE_N domain, with SNARE binding molecular function. The gene is associated with vesicle fusion, intra-Golgi transport, retrograde transport from endosome to Golgi, and Golgi-to-vacuole transport. It is linked to appressorium-mediated host invasion, defense response, macroautophagy, secretion, and homeostasis. The protein localizes to the Golgi membrane, vacuolar membrane, late endosome membrane, COPII-coated vesicle membrane, and SNARE complex. Phenotypic associations include abnormal vacuolar morphology and distribution, increased sporulation, altered adhesion, defective endocytosis, absent protein secretion, and increased ionic stress resistance. Related genes in other species link the family to protein transport, cell cycle progression, and filamentous growth.