MPG1 — Magnaporthe oryzae 70-15

Summary

MGG_01288 (MPG1) on chromosome 2 of Magnaporthe oryzae 70-15 encodes a GDP-mannose pyrophosphorylase with GTP:mannose-1-phosphate guanylyltransferase activity (EC 2.7.7.13). The gene is associated with infection structure formation, appressorium maturation, spore wall biogenesis, cell wall organization, melanin anabolism, secretion, autolysis, sporulation, and host invasion. It is linked to cell cycle progression, cytokinesis, chromosome segregation, endocytosis, autophagy, apoptosis, cell wall morphology, and pseudohyphal growth. Localization evidence connects the product to the yeast-form cell wall, plasma membrane, cytoplasm, and cytosol. Studies of related genes in other species link the family to reduced virulence and oxidative stress response.