CPP1 — Magnaporthe oryzae 70-15

Summary

MGG_01287 (MoCPP1, also known as MoRAM1) on chromosome 2 of Magnaporthe oryzae 70-15 encodes a protein with domains including FTB, PFTB repeat, PGGT1B-like, and Terpenoid_cyclase/PrenylTrfase. The product is annotated with protein farnesyltransferase, GGTaseI, and GGTaseII activities, small GTPase binding, and zinc binding, and localizes to the cytoplasm, nucleus, and farnesyltransferase and geranylgeranyltransferase complexes. MoCPP1 is associated with protein geranylgeranylation, farnesylation, establishment of protein localization to the plasma membrane, appressorium formation, invasive growth, sporulation, hyphal growth, and ER-to-Golgi transport. The gene has been linked to rice blast disease and barley infection. Studies of related genes in other species connect the family to mating efficiency, pheromone production and sensitivity, sporulation, cell cycle progression, pseudohyphal growth, apoptosis, lifespan, cell wall morphology, chitin deposition, and stress resistance.