ILV6 — Magnaporthe oryzae 70-15

Summary

MGG_01104 (MoILV6) in Magnaporthe oryzae 70-15 on chromosome 5 encodes a protein with acetolactate synthase regulator activity and acetolactate synthase activity, and contains acetolactate synthase small subunit and ACT-like domains. The gene is associated with branched-chain amino acid biosynthesis, including valine, isoleucine, and leucine anabolism, as well as appressorium formation and morphogenesis. It localises to the acetolactate synthase complex, cytoplasm, and mitochondrial nucleoid. MoILV6 is linked to numerous phenotypes including abnormal colony colour, increased cell death, abnormal cytokinesis, decreased osmotic stress resistance, absent sporulation, altered cell size, increased mutation frequency, and decreased telomere length. The gene also shows connections to mitochondrial genome maintenance, fermentative metabolism, and respiratory metabolism. Studies of related genes in other species link the family to vacuolar morphology and chemical compound accumulation.