SUM1 — Magnaporthe oryzae 70-15

Summary

MGG_01013 (SUM1, also known as TIF34) encodes a WD40-repeat-containing protein with translation initiation factor activity and RNA binding, and is a component of the eukaryotic translation initiation factor 3 complex. In Magnaporthe oryzae, the gene is associated with appressorium formation and maturation, cell morphogenesis, cytoplasmic translation initiation complex assembly, glycogenolysis, lipolysis, and NO storage. It localises to the nuclear periphery and several translation initiation complexes. Phenotypic associations include decreased invasive growth, absent vegetative growth, abnormal cell cycle progression and cellular morphology, increased desiccation resistance, decreased biofilm formation, and altered filamentous growth. Related genes in other species link the family to translation initiation control.