PEX19 — Magnaporthe oryzae 70-15

Summary

MGG_00971 (MoPEX19) on chromosome 5 of Magnaporthe oryzae 70-15 encodes a protein with a Pex19_C_sf domain that binds the peroxisomal membrane targeting signal (mPTS). The gene is associated with peroxisome membrane protein import, the glyoxylate cycle, and morphogenesis, and its product localises to the peroxisome membrane. MoPEX19 has been linked to numerous phenotypes including absent peroxisomal transport and morphology, abnormal colony shape, decreased chitin deposition, increased hyperosmotic stress resistance, and altered mitophagy, cell cycle progression, and mitochondrial genome maintenance. Related genes in other species link the PEX19 family to peroxins PEX10, PEX12, and PEX13.