SUB1 — Magnaporthe oryzae 70-15

Summary

MGG_00780 (MoSUB1) on chromosome 5 of Magnaporthe oryzae 70-15 encodes a protein belonging to the Sub1/Tcp4-like family, containing a PC4_C domain and an ssDNA-binding transcriptional regulator domain. The product has transcription coactivator activity, binds double-stranded and single-stranded DNA, and is associated with positive regulation of RNA polymerase II transcription initiation, DNA repair, and DNA-dependent transcription. It localises to the nucleus and transcription regulator complexes. The gene is linked to the PC4 coactivator family. Studies of related genes in other species connect the family to transcriptional coactivation, though these associations are not established for MoSUB1 itself.