ABC2 — Fusarium graminearum PH-1

Summary

FgABC2 (FGRAMPH1_01G23403) on chromosome 4 of Fusarium graminearum PH-1 encodes an ABC-type oligopeptide transporter with ATP hydrolase activity, belonging to the type 1 exporter family and containing ABC transporter-like ATP-binding and transmembrane domains. The gene is associated with oligopeptide export from the mitochondrion, sterol anabolism, secretion, membrane transport, and homeostasis, and its product localises to the mitochondrial inner membrane, plasma membrane, and general membrane. Phenotypic associations include altered oxidative and hypo-osmotic stress resistance, abnormal vacuolar morphology and distribution, increased pexophagy, decreased endocytosis, abnormal cell cycle progression, and changes in fermentative metabolism and entry into stationary phase. The gene is also linked to the related genes TLC1, NFT1, and MDL1. Sequence similarity links extend to traits such as leaf width and salt tolerance in other species.