ptr2 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G24235 (ptr2) on chromosome 4 of Fusarium graminearum PH-1 encodes a member of the POT (proton-coupled oligopeptide transporter) family, which belongs to the major facilitator superfamily (MFS) and possesses tripeptide and dipeptide transmembrane transporter activity. The gene is associated with perithecium development, oligopeptide transport, and the import of di- and tripeptides across the plasma membrane, as well as with downregulation of TORC1 signaling and protein transport. Its product localizes to the plasma membrane at cell tips, the fungal-type vacuole and its membrane, and cell division sites. The gene is linked to numerous other loci, including spj1, tcg1, and TUP1. Studies of related genes in other species connect the family to germination rate and oxidative stress response.