ABC2 — Fusarium graminearum PH-1

Summary

FgABC2 (FGRAMPH1_01G24527) on chromosome 4 of Fusarium graminearum PH-1 encodes an ABC transporter with cadmium ion transmembrane transporter, haem-transporting ATPase, and ABC-type phytochelatin transporter activities, and binds ATP, heme, and metals. It is associated with heme export from the vacuole to the cytoplasm, cellular detoxification of cadmium ions, glutathione and PC2 import into the vacuole, xenobiotic detoxification via plasma membrane export, cichorine and sterol anabolism, homotypic vacuole fusion, filamentous growth in response to starvation or biotic stimulus, secretion, membrane transport, interaction with the host, and response to metal. The protein localizes to the fungal-type vacuole membrane, Golgi complex, plasma membrane, extracellular vesicles, and the extracellular space.