laeA — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G25325 (laeA) on chromosome 4 of Fusarium graminearum PH-1 encodes a protein belonging to the SAM-dependent methyltransferase superfamily and is annotated with methyltransferase activity. The gene is associated with regulation of secondary metabolism, secondary metabolite biosynthesis, activation of gliotoxin anabolism, ergosterol anabolism, spore formation, disruption of host phagocytosis, DNA-dependent transcription, and methylation. The product localizes to the nucleus. Related genes in other species link the family to the regulation of secondary metabolite production and pathogenicity.