ORLA — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G25999 (ORLA, also known as TPS2) in Fusarium graminearum PH-1 encodes a protein with trehalose synthase activity, trehalose-phosphatase activity, and transglucosylase activity, containing Glyco_trans_20 and Trehalose_PPase domains. The gene is associated with trehalose biosynthesis and metabolism, as well as cellular responses to desiccation, heat, and general stress. It is linked to sexual reproduction, ascospore formation, sporulation, filamentous growth in response to heat and biotic stimuli, lateral growth, fungal-type cell wall organization, chitin anabolism, secondary metabolism including mycotoxin anabolism, the TCA cycle, and cell death. The protein localizes to the trehalose-6-phosphate synthase complex, cytosol, and nucleus. Associations with numerous phenotypes include increased acquired thermotolerance, freeze-thaw resistance, starvation resistance, and survival in stationary phase, along with absent spore germination, abnormal mating response, delayed meiosis, and decreased nuclear size.