ZEB1 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G25715, symbol ZEB1, on chromosome 4 of Fusarium graminearum PH-1, encodes a FAD-linked oxidoreductase of the berberine bridge enzyme (BBE) family, possessing isomerase activity, FAD binding, and redox activity. The gene is associated with the zearalenone biosynthetic process, patulin anabolism, and alkaloid metabolism, and its product localises to the vacuolar lumen, fungal-type vacuole lumen, vacuole, and extracellular. ZEB1 is also linked to mycotoxin content. Studies of related genes in other species connect the family to additional oxidoreductase functions, though these associations are not established for this specific gene.