REP1 — Candida albicans

Summary

CR_00140W_A (REP1) on Candida albicans chromosome 8 encodes a DNA-binding transcription factor with a p53-like DNA-binding domain and an NDT80 DNA-binding domain, and is annotated with galactose binding activity. The gene is associated with the regulation of transcription by RNA polymerase II, including positive regulation, and is linked to sexual reproduction, biofilm formation, hyphal growth, filamentous growth, morphogenesis, the meiotic cell cycle, and cell death. It is also associated with N-acetylglucosamine breakdown, galactose metabolism, and upregulation of transcription from RNA polymerase II promoter by galactose, as well as the cellular response to xenobiotic stimulus. The product localizes to the nucleus and nuclear chromosome. Additionally, REP1 has been associated with glucose content.